Spotlight On CBDA & Delta-8-THC

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Hemp and cannabis offer many different health and wellness benefits but it’s sometimes difficult for patients and consumers to know which cannabinoid does what.

Here, we’re going to look at the specific potential benefits of CBDA and Delta-8-THC for nausea, pain and inflammation, stress relief and mood improvement. 

Introducing CBDA and Delta-8-THC

CBDA (cannabidiolic acid) is the botanical precursor to CBD (cannabidiol). Like CBD, it is not psychoactive and can therefore be taken at any time of day or in any situation. 

Delta-8-THC (Delta-8-tetrahydrocannabinol) is close cousin of “regular” THC and can be psychoactive. Delta-8-THC is considered to be about half to two-thirds as intoxicating as THC and offers a more upbeat, functional high with less risk of anxiety or paranoia. This makes it more ideal than THC for therapeutic uses, however, do not drive a vehicle or operate machinery while taking Delta-8-THC. 

Study: CBDA Increases Serotonin, Preventing Nausea

CBDA and Delta-8-THC are both commonly used for nausea relief. Let’s see how they work.

CBDA has been found to activate 5-HT1A serotonin receptors. Serotonin plays a big role in mood regulation. In addition to making us happy, serotonin is also involved in physiological functions including nausea, vomiting and intestinal functions. 

This study shows how CBDA binds with 5-HT1A serotonin receptors more strongly than CBD and therefore suppresses nausea and vomiting caused by both motion sickness and toxins better than CBD.

In this experiment, rats were given a very low dose of CBDA. The cannabinoid was found to suppress acute nausea on its own and also improve the effects of a common anti-nausea drug. 

A separate scientific study on CBDA found that it significantly reduced nausea, vomiting and anticipatory nausea (which occurs when a chemotherapy patient vomits at the sight of a treatment room.) The experiment found that CBDA was a far more potent antiemetic than CBD (cannabidiol).

Delta-8-THC Stops Nausea in Study on Child Cancer Patients

Meanwhile, cancer patients have long turned to cannabis to reduce nausea and vomiting during chemotherapy sessions.  While, THC from cannabis can be an effective antiemetic, the powerful high it produces can be overwhelming.

Delta-8-THC can be a better alternative, offering anti-nausea properties without being as intoxicating. 

In this experiment, Delta-8-THC was given to pediatric cancer patients undergoing chemotherapy. Amazingly, Delta-8-THC prevented the children from vomiting in all 480 chemotherapy sessions. 

Study: CBDA Works For Inflammation Like NSAIDS

Cannabis and hemp products are often used by people hoping to treat pain and inflammation. 

CBDA appears to especially useful for inflammation and pain associated with swelling. This is because CBDA has a very similar chemical structure to non steroidal anti-inflammatory drugs (NSAIDS). Like NSAIDS, it inhibits COX-2 receptors and holds promse as a powerful anti-inflammatory agent. See how CBDA works like NSAIDS.

Delta-8-THC Studied for Pain, GI Issues

Like THC, Delta-8-THC is believed to reduce pain and inflammation. In this 2018 study, Delta-8-THC was found to decrease corneal pain and inflammation in an experiment on mice. 

Delta-8-THC could be especially helpful for people with gastrointestinal issues (GI) such as irritable bowel syndrome (IBS). This study demonstrates and details how Delta-8-THC “could be beneficial in functional bowel disorders such as IBS).

Studies on CBDA and Delta-8-THC for Stress, Anxiety, and Mood

Both CBDA and Delta-8-THC are incredible cannabinoids for stress resilience. 

CBDA has been found to improve mood by binding with serotonin receptors more strongly than CBD.

Meanwhile, Delta-8-THC binds with CB1 receptors which can induce a euphoric feeling of happiness.

CBC (cannabichromene) can also be an excellent addition for improving mood without getting high. CBC is especially good at raising anandamide levels. Anandamide is the brain’s “bliss” molecule, responsible for creating feelings of pleasure. Read more about CBC and Terpenes for Happiness and Focus here. 

You can also learn more from our blogs here:

CBDA vs. CBD. What is CBDA and what is it good for?

What is Delta-8-THC?

How to take CBDA and Delta-8-THC

Rare Cannabinoid Company offers an apothecary of cannabinoids for you to mix and match according to your needs. 

We believe in the “entourage effect,” which means that cannabinoids work even better when taken together. Taking one alone is akin to taking a Vitamin C pill on its own. Taking a full spectrum product or multiple cannabinoids together is akin to getting all the benefits of eating a whole orange. 

We therefore recommend taking CBDA or Delta-8-THC with our full spectrum Rare Hawaiian CBD, with other rare cannabinoids – THCV, CBG, CBC, CBN – or with your own favorite full or broad spectrum CBD or THC oil.

This is a great way to enhance your cannabinoid regime and get the targeted benefits of specific rare cannabinoids and the “entourage effect.” 

Learn more and buy CBDA here.

Learn more and buy Delta-8-THC here.